Adaptation in response to the local pathogenic environment

Matteo Fumagalli, our local pendant to Marcello Mastroianni, published a new paper in PLoS Genetics arguing that the pathogenic environment is the strongest driver of local adaptation in humans.  He also shows that the set of genes involved in local adaptation is enriched with genes related to auto-immune diseases – also relative to other disease genes.  Something we found interesting in the light of various evolutionary hypotheses regarding the origin and causes of auto-immune diseases.  Both Nature and Nature Review Genetics agreed that this was interesting and wrote news stories about it.  You can find the stories here, here, and here.

 

 

 

1 Comment

Leave a Reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <s> <strike> <strong>